Get on this!
Seriously though, after reading that excellent piece by remediosvaro, I got to thinkin' "how could del Toro possibly follow up with Pacific Rim?" The answer came to me in a flash, Big Guy and Rusty the Boy Robot! I mean think about it. Giant robots? Check. Giant aliens? Check. What's not to love?
From what I remember watching this on Fox Kids as a, err, kid, the plot was pretty simple. Big Guy is a mech suit piloted by some guy and Rusty is a fully autonomous robot with the personality of a young boy. They work for some secret government group dedicated to stopping various threats that come in the forms of monsters/aliens/alien monsters. The kicker is that Rusty doesn't actually know Big Guy has a human pilot, he thinks it's a robot just like him. And with that, drama and explosions ensue.
A quick look at the wiki page tells me that this was early Frank Miller and even then it was a bit too "Hoo-ra! USA!" but I'm sure GDT could hammer all that out. It will probably never happen but hey, I can dream can't I?