Entertainment Weekly just posted an interview with Orphan Black creators John Fawcett and Graeme Manson about some of what Season 2 is going to hold. They've also released the first official image. Possible mild spoilers below.
EW: Season 1 on any show is all about introducing the story and the characters, and it's essentially setting the table. And if you do it right, a lot people want to come sit down at that table. But now, in season 2 what do you do to keep them sitting there?
MANSON: Right off the bat we've really hit the ground running. We left a lot up in the air, so it's been a lot of fun figuring out how and when and where those balls land and how they land in unexpected ways. As for Rachel, we did leave last season knowing that Rachel was a child of Neolution, therefore much connected to the origins of the experiment. So I think Rachel is going to help to open a window for us and we 're going to begin to understand a lot more about the conspiracy.
FAWCETT: Plus, I also think one of the big things we're going to have to deal with in season 2, which is finding its own twists and turns, is Cosima's illness. And that is a very pressing bit of drama that is not just straight ahead. It's got a lot of mystery to it. It's got a lot of twists and turns to it and it is thematically a big part of season 2 also.
The full interview is worth checking out.