Spoilers... sort of... after the cut...
1) Skye: all the "nice-nice"... and yet another mention of 'mom and dad' (this time as an analogy, but still)... something's up with her, and not the obvious 'hacker fromt he Red Tide" sort of wrong, either.
2) Coulson: once again reminded he's been 'changed'... but nothing more? Dangling that thread a wee bit too much, i think.
3) May: headstrong... maybe that's what made her stop being active in the field to begin with, if she runs off half-cocked like that.
4) This implant thing is going to come back and factor in later.
5)Lastly: don't do the pseudo-post-credits bit if it is always going for the gag. This week's cut was weak. Seriously, how could you top the Nick Fury cameo?