I hadn't seen news of this around the Gawker/Kinja-verse as of yet, so thought I'd share.
EDIT: As Balmut pointed out it has only been speculated that Janet van Dyne (The Wasp) is Pym's wife and may already be dead in the upcoming Ant-Man film. The 'tragedy' is said to involve Pym's wife and daughter (Hope). Also there is further speculation that Hank Pym's daughter, Hope Pym, will *possibly* be a love interest for Scott Lang.
We don't know if either Hope or Cassie will be super-powered or not in the film. In the comics Cassie has a congenital heart disease. It is likely that Cassie will play a role in Scott taking on the mantle of Ant-Man in hopes of 'saving' Cassie in some form or fashion.
I guess we shall see. Funny, I was excited to see this film (up until a couple of months ago) and now I'm on the fence. But who am I kidding? I'll see it.